HEPATITIS B IMMUNE GLOBULIN (HBIG) INFUSION		version 2/27/2025		

Appointment Requests 	

	
	Interval	Defer Until	Duration	
	☑	Referral to IV Infusion Room	Every 4 weeks	S	 treatments	
		Status: Future, Expected: S, Expires: S+365, Clinic Performed
	Urgency of Scheduling: Routine		

Labs 	

	
	Interval	Defer Until	Duration	
	☐	Hepatitis B surface antigen	Every visit	S	Until discont'd	
		STAT, Normal, Clinic Collect		
	☐	Hepatitis B surface antibody	Every visit	S	Until discont'd	
		STAT, Normal, Clinic Collect		

Nursing Orders 	

	
	Interval	Defer Until	Duration	
	☐	Insert Peripheral IV or Access Portacath	Every visit	S	Until discont'd	
		No details available for preview		
	☐	Nursing communication: Contact physician and discontinue HBIG infusion if the patient experiences any of the following symptoms: hypotension, tachycardia, severe myalgias, shortness of breath	Every visit	S	Until discont'd	
		No details available for preview		
	☐	sodium chloride 0.9% flush 10 mL	Every visit	S	Until discont'd	
		10 mL, intravenous, PRN, line care, Starting when released, for 10 doses		
	☐	HEParin, porcine injection 500 Units	Every visit	S	Until discont'd	
		500 Units, intra-catheter, once, Starting when released
	ONLY IF PATIENT HAS PORTACATH: Flush portacath before removing needle from portacath.		
	☐	In Rare Event of Anaphylaxis: **Stop HBIG infusion immediately **Administer 0.3-0.5 mg = 0.3-0.5 mL of the 1:1000 epinephrine subcutaneously **Notify attending physician for advisement immediately	Every visit	S	Until discont'd	
		No details available for preview		
	☐	sodium chloride 0.9% infusion 250 mL	Every visit	S	Until discont'd	
		250 mL, intravenous, at 30 mL/hr, PRN, Flush bag, Starting when released, Until Discontinued		
	☐	Discontinue IV	Every visit	S	Until discont'd	
		No details available for preview		

Pre-Medications 	

	
	Interval	Defer Until	Duration	
	☐	acetaminophen (TYLENOL) tablet 650 mg	Every visit	S	Until discont'd	
		650 mg, oral, once, Starting when released
	Administer 30 minutes before infusion.
	Maximum of 4 grams of acetaminophen per day from all sources. (Cirrhosis patients maximum: 2 grams per day from all sources).		
	☐	diphenhydrAMINE (BENADRYL) tablet 25 mg	Every visit	S	Until discont'd	
		25 mg, oral, once, Starting when released
	Administer 30 minutes before infusion.		

Medications 	

	
	Interval	Defer Until	Duration	
	☐	hepatitis B immune globulin (HEPAGAM B) 9,360 Units in sodium chloride 0.9% 250 mL IVPB	Every 4 weeks	S	Until discont'd	
		9,360 Units, intravenous, Administer over: 3 Hours, once, Starting 30 minutes after treatment start time		

Emergency Medications 	

	
	Interval	Defer Until	Duration	
	☐	epINEPHrine (ADRENALIN) injection 1 mg/mL 0.3-0.5 mg	PRN	S	Until discont'd	
		0.3-0.5 mL, subcutaneous, once PRN, anaphylaxis, Starting when released, Until Discontinued		
	☐	diphenhydrAMINE (BENADRYL) injection 50 mg	PRN	S	Until discont'd	
		50 mg, intravenous, once PRN, anaphylaxis, Starting when released, Until Discontinued		
	☐	hydrocortisone sodium succinate (Solu-CORTEF) injection 100 mg	PRN	S	Until discont'd	
		100 mg, intravenous, once PRN, anaphylaxis, Starting when released, Until Discontinued