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OP RSH PRO00042841 PRATH CCTG-PR26 SCREENING	

Types:      Research Oncology Treatment
Synonyms:  PRO00042841 PRATH CCTG-PR26, CCTG-PR26, STANDARD ADT + ARPI

Pre-study prior to enrollment	Repeat 1 time	Cycle length: 28 days	Within 28 days (-28 to 0)	Perform every 1 day x1			Research tolerance: -0/+0 days	Nursing Orders
  	ONC NURSING COMMUNICATION	Interval: Until discontinued	Occurrences: --	Comments:	Nursing Communication: Please refer to Study Protocol for any questions or discrepancies. See Schedule of Events Calendar for sequence of diagnostic tests, examinations, and treatment administration: See Safety Parameters-for Toxicity Management and Dose Modification Guidelines: Protocol Access hyperlink:     CCTG-PR26_Prath
		  	ONC NURSING COMMUNICATION 34	Interval: --	Occurrences: --	Comments:	This study adheres to the NCI standard practices for streamlined data submission as determined by the Clinical Trials and Translation Research Advisory Committee (CTAC). In accordance with these practices, the patient evaluations below indicate investigations that are required for submission to the clinical trial database. These, however, do not override or otherwise affect participating sites' standard of care and/or practice guidelines for collecting clinical information and recording it in the local medical record
			Imaging
☐	CT CHEST W CONTRAST ABDOMEN W CONTRAST PELVIS W CONTRAST	Interval: --	Occurrences: --	Comments:	Tumor Scan
		☐	CT CHEST WO CONTRAST ABDOMEN WO CONTRAST PELVIS WO CONTRAST	Interval: --	Occurrences: --	Comments:	Tumor Scan
		☑	CT CHEST W CONTRAST ABDOMEN W WO CONTRAST PELVIS W WO CONTRAST	Interval: --	Occurrences: --	Comments:	Tumor Scan
		☐	CT CHEST W WO CONTRAST ABDOMEN W CONTRAST PELVIS W CONTRAST	Interval: --	Occurrences: --	Comments:	Tumor Scan
			Imaging
☐	NM BONE SCAN LIMITED	Interval: --	Occurrences: --		☑	NM BONE SCAN WHOLE BODY	Interval: --	Occurrences: --			Imaging
◯	CT HEAD W CONTRAST	Interval: --	Occurrences: --	Comments:	CT or MRI Brain. Required if known brain metastases or as clinically indicated
		◉	MRI BRAIN W CONTRAST	Interval: --	Occurrences: --	Comments:	CT or MRI Brain. Required if known brain metastases or as clinically indicated
				Within 14 days (-14 to 0)	Perform every 1 day x1			Research tolerance: -0/+0 days	Nursing Orders
  	ONC NURSING COMMUNICATION	Interval: Until discontinued	Occurrences: --	Comments:	Nursing Communication: Please refer to Study Protocol for any questions or discrepancies. See Schedule of Events Calendar for sequence of diagnostic tests, examinations, and treatment administration: See Safety Parameters-for Toxicity Management and Dose Modification Guidelines: Protocol Access hyperlink:     CCTG-PR26_Prath
			Nursing Orders
  	ONC NURSING COMMUNICATION 35	Interval: --	Occurrences: --	Comments:	History and Physical exam (includes height at baseline only, weight). Visit may be conducted by phone or virtually
		  	ONC NURSING COMMUNICATION 36	Interval: --	Occurrences: --	Comments:	ECOG PS. Visit may be conducted by phone or virtually
		  	ONC NURSING COMMUNICATION 37	Interval: --	Occurrences: --	Comments:	Adverse events assessment. CTCAE Grade Greater than or EQUAL to 3 ( >= 3). Visit may be conducted by phone or virtually
			Labs
  	AST (SGOT)	Interval: --	Occurrences: --		  	ALT (SGPT)	Interval: --	Occurrences: --		  	ABSOLUTE NEUTROPHIL COUNT	Interval: --	Occurrences: --		  	PLATELET COUNT	Interval: --	Occurrences: --		  	HEMOGLOBIN	Interval: --	Occurrences: --		  	BILIRUBIN DIRECT	Interval: --	Occurrences: --		  	ALKALINE PHOSPHATASE	Interval: --	Occurrences: --		  	CREATININE CLEARANCE, URINE, 24 HOUR	Interval: --	Occurrences: --		  	PROSTATE SPECIFIC ANTIGEN	Interval: --	Occurrences: --		  	TESTOSTERONE, TOTAL AND FREE, IMMUNOASSAY AND CALCULATION (FOR ADULT MALES)	Interval: --	Occurrences: --				Within 5 days of randomization	Perform every 1 day x1			Research tolerance: -0/+0 days	Research Labs
  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --	Comments:	Whole blood (for ctDNA). Both arms. For Arm 2, this should be before the first dose of docetaxel
				Pre-study prior to enrollment	Perform every 1 day x1			Research tolerance: -0/+0 days	Research Labs
  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --	Comments:	Archival tissue blocks. Optional for consenting participants