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OP RESEARCH PRO00038509 C2321014 SCREENING EFSTATHIOU	

Types:      Research Oncology Treatment
Synonyms:  

Cycle 1	Repeat 1 time	Cycle length: 1 day	Day 1	Perform every 1 day x1		Provider Communication
  	ONC PROVIDER COMMUNICATION	Interval: --	Occurrences: --	Comments:	Nursing Communication: Please refer to Study Protocol for any questions or discrepancies. See Schedule of Events Calendar for sequence of diagnostic tests, examinations, and treatment administration: See Safety Parameters-for Toxicity Management and Dose Modification Guidelines: Protocol Access hyperlink:   C2321014 _Efstathiou
		  	ONC PROVIDER COMMUNICATION 2	Interval: --	Occurrences: --	Comments:	Nursing Communication: Dose Modifications and Management for PF-06821497, enzalutamide and docetaxel Treatment: Refer to Section 6.6 (Dose Modification): Protocol Access Hyperlink:  C2321014 _Efstathiou
			Nursing Orders
  	ONC NURSING COMMUNICATION 2	Interval: --	Occurrences: --	Comments:	Informed Consent
		  	ONC NURSING COMMUNICATION 5	Interval: --	Occurrences: --	Comments:	Screen for inclusion/exclusion criteria
		  	ONC NURSING COMMUNICATION 6	Interval: --	Occurrences: --	Comments:	Demographics
		  	ONC NURSING COMMUNICATION 8	Interval: --	Occurrences: --	Comments:	Medical History: Relevant medical and surgical history, and current illnesses. Includes histology, TNM classification, Gleason score
		  	ONC NURSING COMMUNICATION 9	Interval: --	Occurrences: --	Comments:	Physical Exam
		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --	Comments:	Measure blood pressure, heart rate, temperature (Celsius)
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --	Comments:	Measure height (cm) (screening only) and weight (kg)
		  	ONC NURSING COMMUNICATION 10	Interval: --	Occurrences: --	Comments:	ECOG Performance Status
		  	ONC NURSING COMMUNICATION 11	Interval: --	Occurrences: --	Comments:	Contraception check
		  	ONC NURSING COMMUNICATION 12	Interval: --	Occurrences: --	Comments:	Counseling to seek advice about donation and cryopreservation of sperm cells prior to start of study
		  	ONC NURSING COMMUNICATION 14	Interval: --	Occurrences: --	Comments:	Prior/concomitant treatment(s)
		  	ONC NURSING COMMUNICATION 15	Interval: --	Occurrences: --	Comments:	Serious/nonserious AE monitoring: Report serious and non-serious adverse event information from time informed consent form is signed through screen failure or through a minimum of 28 days after the last dose of study intervention.
		  	ONC NURSING COMMUNICATION 16	Interval: --	Occurrences: --	Comments:	Symptomatic Skeletal Events
		  	ONC NURSING COMMUNICATION 20	Interval: --	Occurrences: --	Comments:	BPI-SF, FACT-P, EQ-5D-5L
		  	ONC NURSING COMMUNICATION 22	Interval: --	Occurrences: --	Comments:	PRO-CTCAE and FACT-GP5
		  	ECG 12-LEAD	Interval: --	Occurrences: --			Procedures
  	BIOPSY	Interval: --	Occurrences: --	Comments:	Screening Tumor Biopsy: Only required if no prior histological or cytological confirmation of prostrate adenocarcinoma is available.
			Labs
  	CBC WITH PLATELET AND DIFFERENTIAL	Interval: --	Occurrences: --		  	ABSOLUTE NEUTROPHIL COUNT	Interval: --	Occurrences: --		  	COMPREHENSIVE METABOLIC PANEL	Interval: --	Occurrences: --		  	LDH	Interval: --	Occurrences: --		  	PHOSPHORUS LEVEL	Interval: --	Occurrences: --		  	CYSTATIN C WITH EGFR	Interval: --	Occurrences: --		  	CD 4 SUBSET	Interval: --	Occurrences: --	Comments:	CD4 count to be obtained if lymphocyte count is <500 microliter
		  	TESTOSTERONE, TOTAL AND FREE+BIOAVAILABLE, IMMUNOASSAY AND CALCULATION (FOR ADULT MALES)	Interval: --	Occurrences: --		  	PSA, TOTAL AND FREE	Interval: --	Occurrences: --			Imaging
  	CT CHEST W CONTRAST ABDOMEN W CONTRAST PELVIS W CONTRAST	Interval: --	Occurrences: --	Comments:	If MRI of abdomen and/or pelvis is desired, please place order. 
-42 days accepted.
		  	NM BONE SCAN WHOLE BODY	Interval: --	Occurrences: --	Comments:	Whole body bone scan: Tc- 99m Bone Scintigraphy. 
-42 days accepted.