Protocol Index	

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OP RESEARCH PRO00035985 EA9181 NCT04530565 STEP 3 PRE-REGISTRATION SHAH	

Types:      Research Oncology Treatment
Synonyms:  

Cycle 1	Repeat 1 time	Cycle length: 1 day	Day 1	Perform every 1 day x1		Nursing Orders
  	ONC NURSING COMMUNICATION 2	Interval: --	Occurrences: --	Comments:	Physical Examination - prior to registration
		  	ONC NURSING COMMUNICATION 5	Interval: --	Occurrences: --	Comments:	AEs - prior to registration
		  	ECG 12-LEAD	Interval: --	Occurrences: --	Comments:	prior to registration
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --	Comments:	prior to registration
			Labs
  	CBC WITH PLATELET AND DIFFERENTIAL	Interval: --	Occurrences: --	Comments:	To be completed LESS than or EQUAL to 24 hours before registration.
		  	ABSOLUTE NEUTROPHIL COUNT	Interval: --	Occurrences: --	Comments:	To be completed LESS than or EQUAL to 24 hours before registration.
		  	COMPREHENSIVE METABOLIC PANEL	Interval: --	Occurrences: --	Comments:	Prior to registration
		  	URIC ACID LEVEL	Interval: --	Occurrences: --		  	PHOSPHORUS LEVEL	Interval: --	Occurrences: --	Comments:	Prior to registration
		  	MAGNESIUM LEVEL	Interval: --	Occurrences: --	Comments:	Prior to registration
		  	BILIRUBIN DIRECT	Interval: --	Occurrences: --	Comments:	Prior to registration
		  	LDH	Interval: --	Occurrences: --	Comments:	Prior to registration
		  	AMYLASE LEVEL	Interval: --	Occurrences: --	Comments:	Prior to registration
		  	LIPASE LEVEL	Interval: --	Occurrences: --	Comments:	Prior to registration
		  	PROTHROMBIN TIME WITH INR	Interval: --	Occurrences: --	Comments:	Prior to registration
		  	PARTIAL THROMBOPLASTIN TIME (PTT)	Interval: --	Occurrences: --	Comments:	Prior to registration
		  	FIBRINOGEN	Interval: --	Occurrences: --	Comments:	Prior to registration
		  	D-DIMER	Interval: --	Occurrences: --	Comments:	Prior to registration
			Appointment Requests
  	IR LUMBAR PUNCTURE	Interval: --	Occurrences: --	Comments:	To be done prior to registration.
			Procedures
  	BIOPSY BONE MARROW	Interval: --	Occurrences: --	Comments:	o To be done prior to registration. 
o Bone Marrow Aspirate, and Biopsy - Submit two (2) original karyotypes per clone, FISH results, institution's cytogenetic laboratory report, and the Leukemia Cytogenetic Form (#365R) via Medidata Rave. Cytogenetics are only required at time of initial diagnosis and are optional at all later time points. Direct questions to Sarina Sherpa at Tel: (212) 639-8835.
			Labs
  	FLOW CYTOMETRY EVALUATION	Interval: --	Occurrences: --	Comments:	o To be done prior to registration.  
o Submit two (2) original karyotypes per clone, FISH results, institution's cytogenetic laboratory report, and the Leukemia Cytogenetic Form (#365R) via Medidata Rave. Cytogenetics are only required at time of initial diagnosis and are optional at all later time points. Direct questions to Sarina Sherpa at Tel: (212) 639-8835.
		  	CYTOLOGY (NON-GYNECOLOGICAL) REQUEST	Interval: --	Occurrences: --	Comments:	o To be done prior to registration.  
o Cytogenetics - Submit two (2) original karyotypes per clone, FISH results, institution's cytogenetic laboratory report, and the Leukemia Cytogenetic Form (#365R) via Medidata Rave. Cytogenetics are only required at time of initial diagnosis and are optional at all later time points. Direct questions to Sarina Sherpa at Tel: (212) 639-8835.