Protocol Index	

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OP RESEARCH H-42712 MAPSS	

Types:      Research Oncology Treatment
Synonyms:  H42712

Cycle 1	Repeat 1 time	Cycle length: 1827 days	Day -1	Perform every 1 day x1		Labs
  	COMPREHENSIVE METABOLIC PANEL	Interval: --	Occurrences: --		  	CBC WITH PLATELET AND DIFFERENTIAL	Interval: --	Occurrences: --		  	LDH	Interval: --	Occurrences: --		  	HCG QUALITATIVE, SERUM SCREEN	Interval: --	Occurrences: --	Comments:	ONLY if applicable.
		  	SERUM ELECTROPHORESIS	Interval: --	Occurrences: --		  	BETA-2 MICROGLOBULIN	Interval: --	Occurrences: --		  	IMMUNOGLOBULIN G	Interval: --	Occurrences: --		  	IMMUNOGLOBULIN A	Interval: --	Occurrences: --		  	IMMUNOGLOBULIN M	Interval: --	Occurrences: --		  	KAPPA LAMBDA FREE LIGHT CHAIN WITH RATIO	Interval: --	Occurrences: --			Nursing Orders
  	ONC NURSING COMMUNICATION 9	Interval: --	Occurrences: --	Comments:	Please provide 24-hour urine collection container to patient to return on Day 0 visit.
				Day 0	Perform every 1 day x1		Nursing Orders
  	ONC NURSING COMMUNICATION 5	Interval: --	Occurrences: --	Comments:	Verify vaccine dose and patient information on Component Infusion Form.
		  	ONC NURSING COMMUNICATION 10	Interval: --	Occurrences: --	Comments:	Obtain history and physical.
		  	INSERT PERIPHERAL IV	Interval: --	Occurrences: --	Comments:	If no central line
		  	ONC NURSING COMMUNICATION 2	Interval: --	Occurrences: --	Comments:	Please provide to patient the following item: Stool culture containers with instruction on how to collect specimen.  Patient will return stool culture container on Day 4 visit.
		  	ONC NURSING COMMUNICATION 6	Interval: --	Occurrences: --	Comments:	Vaccine to be administered by physician. Clinic nurse to remain at bedside during the entire vaccination.
		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --	Comments:	Including breath sounds. Monitor and record: Pre-vaccination, during vaccination, post vaccination, and then every 1 hour for 3 hours.
		  	PULSE OXIMETRY	Interval: --	Occurrences: --	Comments:	Monitor and record: Pre-vaccination, during vaccination, post vaccination, and then every 1 hour for 3 hours.

Monitor continuous pulse oximeter for 30 minutes after completion of oral vaccination.
		  	RESEARCH - SUPPLIES/KIT TO BEDSIDE	Interval: --	Occurrences: --	Comments:	Must be at bedside prior to infusion: Oxygen and suction set up, normal saline flushes, red caps, and syringes with needles (1mL and 3 mL).
		  	RESEARCH - ASSESS	Interval: --	Occurrences: --	Comments:	Patient for immediate reactions: 1) Allergic reactions (anaphylaxis) 2) Decreased oxygenation (due to migration of lymphocytes to lungs).
			Labs
  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --		  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --			Labs
  	URINE PROTEIN ELECTROPHORESIS, 24 HOUR	Interval: --	Occurrences: --			Pre-Medications
  	ONC NURSING COMMUNICATION 8	Interval: --	Occurrences: --	Comments:	Premeds on call for infusion: Please order as soon as labs are sent.
		  	sodium bicarbonate tablet 1,950 mg	Dose: 1,950 mg	Route: oral	once for 1 dose	Start: S			Instructions:	Administer approximately 10 minutes prior to receiving the vaccine to assist with the absorption of the vaccine.
Dissolve tablet completely in a glass of water before administering.			Emergency Medications
  	TRANSFUSION REACTION EVALUATION	Interval: Once	Occurrences: --	Comments:	Emergency Medications: Anaphylactic precautions: Keep medications at the bedside to administer per physician's orders.
		  	diphenhydrAMINE (BENADRYL) injection 50 mg	Dose: 50 mg	Route: intravenous	once PRN	Start: S			Instructions:	Keep at the bedside to administer per physician's orders.		  	hydrocortisone sodium succinate (Solu-CORTEF) injection 250 mg	Dose: 250 mg	Route: intravenous	once PRN	Start: S			Instructions:	Keep at the bedside to administer per physician's orders.		  	epINEPHrine (ADRENALIN) 1 mg/1 mL injection 0.3 mg	Dose: 0.3 mg	Route: subcutaneous	once PRN	Start: S			Instructions:	Keep at the bedside to administer per physician's orders.			Discharge Nursing Orders
☑	sodium chloride 0.9 % flush 20 mL	Dose: 20 mL	Route: intravenous	PRN					☑	HEParin, porcine (PF) injection 500 Units	Dose: 500 Units	Route: intra-catheter	once PRN	Start: S			Instructions:	Concentration: 100 units/mL. Heparin flush for Implanted Vascular Access Device maintenance.			Discharge Nursing Orders
  	ONC NURSING COMMUNICATION 76	Interval: --	Occurrences: --	Comments:	Discontinue IV.
				Day 4	Perform every 1 day x1		Nursing Orders
  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --		  	ONC NURSING COMMUNICATION 16	Interval: --	Occurrences: --	Comments:	Please provide stool culture container to patient to return on Week 1 visit
			Labs
  	BLOOD CULTURE, AEROBIC & ANAEROBIC	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
		  	STOOL CULTURE	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
				Day 7	Perform every 1 day x1		Nursing Orders
  	ONC NURSING COMMUNICATION 11	Interval: --	Occurrences: --	Comments:	Obtain history
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --		  	ONC NURSING COMMUNICATION 12	Interval: --	Occurrences: --	Comments:	Please provide stool culture container to patient to return on Week 2 visit.
			Labs
  	CBC WITH PLATELET AND DIFFERENTIAL	Interval: --	Occurrences: --		  	COMPREHENSIVE METABOLIC PANEL	Interval: --	Occurrences: --			Labs
  	BLOOD CULTURE, AEROBIC & ANAEROBIC	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
		  	STOOL CULTURE	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
			Labs
  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --				Day 14	Perform every 1 day x1		Nursing Orders
  	ONC NURSING COMMUNICATION 5	Interval: --	Occurrences: --	Comments:	Verify vaccine dose and patient information on Component Infusion Form.
		  	ONC NURSING COMMUNICATION 10	Interval: --	Occurrences: --	Comments:	Obtain history and physical.
		  	INSERT PERIPHERAL IV	Interval: --	Occurrences: --	Comments:	If no central line
		  	ONC NURSING COMMUNICATION 14	Interval: --	Occurrences: --	Comments:	Please provide to patient the following item:  stool culture container with instruction on how to collect specimen.  Patient will return specimen on Week 3 visit.
		  	ONC NURSING COMMUNICATION 6	Interval: --	Occurrences: --	Comments:	Vaccine to be administered by physician. Clinic nurse to remain at bedside during the entire vaccination.
		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --	Comments:	Including breath sounds. Monitor and record: Pre-vaccination, during vaccination, post vaccination, and then every 1 hour for 3 hours.
		  	PULSE OXIMETRY	Interval: --	Occurrences: --	Comments:	Monitor and record: Pre-vaccination, during vaccination, post vaccination, and then every 1 hour for 3 hours.

Monitor continuous pulse oximeter for 30 minutes after completion of oral vaccination.
		  	RESEARCH - SUPPLIES/KIT TO BEDSIDE	Interval: --	Occurrences: --	Comments:	Must be at bedside prior to infusion: Oxygen and suction set up, normal saline flushes, red caps, and syringes with needles (1mL and 3 mL).
		  	RESEARCH - ASSESS	Interval: --	Occurrences: --	Comments:	Patient for immediate reactions: 1) Allergic reactions (anaphylaxis) 2) Decreased oxygenation (due to migration of lymphocytes to lungs).
			Labs
  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --		  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --			Labs
  	BLOOD CULTURE, AEROBIC & ANAEROBIC	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
		  	STOOL CULTURE	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
		  	COMPREHENSIVE METABOLIC PANEL	Interval: --	Occurrences: --		  	CBC WITH PLATELET AND DIFFERENTIAL	Interval: --	Occurrences: --			Pre-Medications
  	ONC NURSING COMMUNICATION 8	Interval: --	Occurrences: --	Comments:	Premeds on call for infusion: Please order as soon as labs are sent.
		  	sodium bicarbonate tablet 1,950 mg	Dose: 1,950 mg	Route: oral	once for 1 dose	Start: S			Instructions:	Administer approximately 10 minutes prior to receiving the vaccine to assist with the absorption of the vaccine.
Dissolve tablet completely in a glass of water before administering.			Emergency Medications
  	TRANSFUSION REACTION EVALUATION	Interval: Once	Occurrences: --	Comments:	Emergency Medications: Anaphylactic precautions: Keep medications at the bedside to administer per physician's orders.
		  	diphenhydrAMINE (BENADRYL) injection 50 mg	Dose: 50 mg	Route: intravenous	once PRN	Start: S			Instructions:	Keep at the bedside to administer per physician's orders.		  	hydrocortisone sodium succinate (Solu-CORTEF) injection 250 mg	Dose: 250 mg	Route: intravenous	once PRN	Start: S			Instructions:	Keep at the bedside to administer per physician's orders.		  	epINEPHrine (ADRENALIN) 1 mg/1 mL injection 0.3 mg	Dose: 0.3 mg	Route: subcutaneous	once PRN	Start: S			Instructions:	Keep at the bedside to administer per physician's orders.			Discharge Nursing Orders
☑	sodium chloride 0.9 % flush 20 mL	Dose: 20 mL	Route: intravenous	PRN					☑	HEParin, porcine (PF) injection 500 Units	Dose: 500 Units	Route: intra-catheter	once PRN	Start: S			Instructions:	Concentration: 100 units/mL. Heparin flush for Implanted Vascular Access Device maintenance.			Discharge Nursing Orders
  	ONC NURSING COMMUNICATION 76	Interval: --	Occurrences: --	Comments:	Discontinue IV.
				Day 21	Perform every 1 day x1		Nursing Orders
  	ONC NURSING COMMUNICATION 11	Interval: --	Occurrences: --	Comments:	Obtain history
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --		  	ONC NURSING COMMUNICATION 15	Interval: --	Occurrences: --	Comments:	Please provide stool culture container to patient to return on next week's visit.
			Labs
  	CBC WITH PLATELET AND DIFFERENTIAL	Interval: --	Occurrences: --		  	COMPREHENSIVE METABOLIC PANEL	Interval: --	Occurrences: --			Labs
  	BLOOD CULTURE, AEROBIC & ANAEROBIC	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
		  	STOOL CULTURE	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
			Labs
  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --				Day 28	Perform every 1 day x1		Nursing Orders
  	ONC NURSING COMMUNICATION 11	Interval: --	Occurrences: --	Comments:	Obtain history
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --		  	ONC NURSING COMMUNICATION 15	Interval: --	Occurrences: --	Comments:	Please provide stool culture container to patient to return on next week's visit.
			Labs
  	CBC WITH PLATELET AND DIFFERENTIAL	Interval: --	Occurrences: --		  	COMPREHENSIVE METABOLIC PANEL	Interval: --	Occurrences: --			Labs
  	BLOOD CULTURE, AEROBIC & ANAEROBIC	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
		  	STOOL CULTURE	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
			Labs
  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --		  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --				Day 35	Perform every 1 day x1		Nursing Orders
  	ONC NURSING COMMUNICATION 11	Interval: --	Occurrences: --	Comments:	Obtain history
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --		  	ONC NURSING COMMUNICATION 15	Interval: --	Occurrences: --	Comments:	Please provide stool culture container to patient to return on next week's visit.
			Labs
  	BLOOD CULTURE, AEROBIC & ANAEROBIC	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
		  	STOOL CULTURE	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
			Labs
  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --				Day 42	Perform every 1 day x1		Nursing Orders
  	ONC NURSING COMMUNICATION 11	Interval: --	Occurrences: --	Comments:	Obtain history
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --		  	ONC NURSING COMMUNICATION 15	Interval: --	Occurrences: --	Comments:	Please provide stool culture container to patient to return on next week's visit.
			Labs
  	CBC WITH PLATELET AND DIFFERENTIAL	Interval: --	Occurrences: --		  	COMPREHENSIVE METABOLIC PANEL	Interval: --	Occurrences: --			Labs
  	BLOOD CULTURE, AEROBIC & ANAEROBIC	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
		  	STOOL CULTURE	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
			Labs
  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --		  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --				Day 49	Perform every 1 day x1		Nursing Orders
  	ONC NURSING COMMUNICATION 11	Interval: --	Occurrences: --	Comments:	Obtain history
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --		  	ONC NURSING COMMUNICATION 20	Interval: --	Occurrences: --	Comments:	Please provide stool culture and 24-hour urine collection container to patient to return on Week 8 visit.
			Labs
  	BLOOD CULTURE, AEROBIC & ANAEROBIC	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
		  	STOOL CULTURE	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
			Labs
  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --				Day 56	Perform every 1 day x1		Nursing Orders
  	ONC NURSING COMMUNICATION 10	Interval: --	Occurrences: --	Comments:	Obtain history and physical.
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --			Labs
  	BLOOD CULTURE, AEROBIC & ANAEROBIC	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
		  	STOOL CULTURE	Interval: --	Occurrences: --	Comments:	Concern for Salmonella infection
			Labs
  	URINE PROTEIN ELECTROPHORESIS, 24 HOUR	Interval: --	Occurrences: --			Labs
  	COMPREHENSIVE METABOLIC PANEL	Interval: --	Occurrences: --		  	CBC WITH PLATELET AND DIFFERENTIAL	Interval: --	Occurrences: --		  	LDH	Interval: --	Occurrences: --		  	HCG QUALITATIVE, SERUM SCREEN	Interval: --	Occurrences: --	Comments:	ONLY if applicable.
		  	SERUM ELECTROPHORESIS	Interval: --	Occurrences: --		  	BETA-2 MICROGLOBULIN	Interval: --	Occurrences: --		  	IMMUNOGLOBULIN G	Interval: --	Occurrences: --		  	IMMUNOGLOBULIN A	Interval: --	Occurrences: --		  	IMMUNOGLOBULIN M	Interval: --	Occurrences: --		  	KAPPA LAMBDA FREE LIGHT CHAIN WITH RATIO	Interval: --	Occurrences: --			Labs
  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --		  	RESEARCH STUDY SPECIMEN	Interval: --	Occurrences: --				Days 90,180	Perform every 90 days x2		Nursing Orders
  	ONC NURSING COMMUNICATION 11	Interval: --	Occurrences: --	Comments:	Obtain history
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --			Labs
  	CBC WITH PLATELET AND DIFFERENTIAL	Interval: --	Occurrences: --		  	COMPREHENSIVE METABOLIC PANEL	Interval: --	Occurrences: --				Day 270	Perform every 1 day x1		Nursing Orders
  	ONC NURSING COMMUNICATION 11	Interval: --	Occurrences: --	Comments:	Obtain history
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --			Labs
  	CBC WITH PLATELET AND DIFFERENTIAL	Interval: --	Occurrences: --		  	COMPREHENSIVE METABOLIC PANEL	Interval: --	Occurrences: --				Days 730,1095,1460,1825	Perform every 365 days x4		Nursing Orders
  	ONC NURSING COMMUNICATION 11	Interval: --	Occurrences: --	Comments:	Obtain history
		  	HEIGHT AND WEIGHT	Interval: --	Occurrences: --		  	VITAL SIGNS - T/P/R/BP	Interval: --	Occurrences: --